Chapter 6: Replication, Maintenance and Rearrangements of Genomic DNA

Animations

The following animations are available for this chapter:

  • 6.1  DNA Replication Fork Helicase, primase, and two molecules of DNA polymerase III carry out the coordinated synthesis of both the leading and lagging strands of DNA at a replication fork.
  • 6.2  Homologous Recombination In the Holliday model for recombination between two homologous double-stranded DNA molecules, the process begins by nicking one strand of each double-stranded molecule, followed by strand exchange and joining of the nicked strands on the opposite molecules.
  • 6.3  Light-Chain Genes During B cell development, site-specific recombination joins regions of the immunoglobulin light-chain genes, leading to the production of unique immunoglobulin light chains.
  • 6.4  Heavy-Chain Genes During B cell development, site-specific recombination joins regions of the immunoglobulin heavy-chain genes, leading to the production of unique immunoglobulin heavy chains.

These animations are in Adobe Flash format. These require the Flash player (version 9 or newer recommended), which can be downloaded free of charge from the Adobe website:
http://www.adobe.com/software/flashplayer/

 

 

 

 

 

 

 

 

 

American Society for Microbiology Sinauer Associates