The Cell: A Molecular Approach

Fourth Edition

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Chapter 6: Replication, Maintenance and Rearrangements of Genomic DNA

Micrograph 6.3  Replication of E. coli DNA

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An autoradiograph showing bacteria that were grown in [³H]thymidine for two generations to label the DNA, which was then extracted and visualized by exposure to photographic film. [From J. Cairns, 1963. Cold Spring Harbor Symp. Quant. Biol. 28: 43.]