Chapter 6: Replication, Maintenance and Rearrangements of Genomic DNA

Micrograph 6.5 Identification of Holliday Junctions by Electron Microscopy

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Electron micrograph of a Holliday junction that was detected during recombination of plasmid DNAs in E. coli. The molecule illustrates a Holliday junction in the open configuration resulting from rotation of the crossed-strand intermediate. [Courtesy of Huntington Potter, University of South Florida, and David Dressler, University of Oxford.]