Decondensed, transcriptionally active interphase chromatin.
exportin
A karyopherin that recognizes nuclear export signals and directs transport from the nucleus to the cytosol.
heterochromatin
Condensed, transcriptionally inactive chromatin.
importin
A karyopherin that recognizes nuclear localization signals and directs nuclear import.
karyopherin
A nuclear transport receptor.
lamin
An intermediate filament protein that forms the nuclear lamina.
nuclear envelope
The barrier separating the nucleus from the cytoplasm, composed of an inner and outer membrane, a nuclear lamina, and nuclear pore complexes.
nuclear export signal
An amino acid sequence that targets proteins for transport from the nucleus to the cytosol.
nuclear lamina
A meshwork of lamin filaments providing structural support to the nucleus.
nuclear localization signal
An amino acid sequence that targets proteins for transportation from the cytoplasm to the nucleus.
nuclear membrane
One of the membranes forming the nuclear envelope; the outer nuclear membrane is continuous with the endoplasmic reticulum and the inner nuclear membrane is adjacent to the nuclear lamina.
nuclear pore complex
A large structure forming a transport channel through the nuclear envelope.
nuclear transport receptor
A protein that recognizes nuclear localization signals and mediates transport across the nuclear envelope.
nucleolar organizing region
A chromosomal region containing the genes for ribosomal RNAs.
nucleolus
The nuclear site of rRNA transcription, processing, and ribosome assembly.
Ran
A small GTP-binding protein involved in nuclear import and export.
small nucleolar RNA (snoRNA)
A small RNA present in the nucleolus that function in pre-rRNA processing.