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• Companion Website
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• Sylvius 4 Website

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Neuroscience

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Neuroscience, Fourth Edition

Edited by Dale Purves, George J. Augustine, David Fitzpatrick, William C. Hall, Anthony-Samuel LaMantia, James O. McNamara, and Leonard E. White

2008
857 pages, 443 illustrations
casebound

About This Title

Neuroscience is a comprehensive textbook created primarily for medical, premedical, and undergraduate students. In a single concise and approachable volume, the text guides students through the challenges and excitement of this rapidly changing field. The book's length and accessibility of its writing are a successful combination that has proven to work equally well for medical students and in undergraduate neuroscience courses. Being both comprehensive and authoritative, the book is also appropriate for graduate and professional use. Key features of the Fourth Edition include:

• Two new chapters. Chapter 8, “Synaptic Plasticity,” offers new and more comprehensive coverage of this important and fast-moving area. Topics covered include mechanisms of short- and long-term synaptic plasticity, such as long-term potentiation and long-term depression. Chapter 25, “Repair and Regeneration in the Nervous System,” focuses on regeneration and stem cells, discussing how the mechanisms currently known to mediate both process regeneration and adult neurogenesis either resemble or diverge from those used during development.
• Thoroughly revised and updated text, including substantial revisions of chapters on the somatic sensory system (Chapter 9), the visual system (Chapters 11 and 12), the chemical senses (Chapter 15), upper motor neuron control (Chapter 17), the basal ganglia (Chapter 19), and sex and sexuality (Chapter 30)
• A free Sylvius 4 download included with every book
• A new appendix presenting an illustrated narrative of human neuroanatomy plus annotated atlas plates presenting brain sections from Sylvius
• Revised and expanded full-color art

Unit Editors

Unit I: George J. Augustine
Unit II: David Fitzpatrick
Unit III: William C. Hall and Leonard E. White
Unit IV: Anthony-Samuel LaMantia
Unit V: Dale Purves
Appendix: S. Mark Williams and Leonard E. White

Contributors

George J. Augustine, Ph.D.
David Fitzpatrick, Ph.D.
William C. Hall, Ph.D.
Anthony-Samuel LaMantia, Ph.D.
James O. McNamara, M.D.
Richard D. Mooney, Ph.D.
Michael L. Platt, Ph.D.
Dale Purves, M.D.
Sidney A. Simon, Ph.D.
Leonard E. White, Ph.D.
S. Mark Williams, Ph.D.

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Table of Contents

1. Studying the Nervous Systems of Humans and Other Animals

Unit I. Neural Signaling

2. Electrical Signals of Nerve Cells
3. Voltage-Dependent Membrane Permeability
4. Channels and Transporters
5. Synaptic Transmission
6. Neurotransmitters, Receptors, and Their Effects
7. Molecular Signaling within Neurons
8. Synaptic Plasticity

Unit II. Sensation and Sensory Processing

9. The Somatic Sensory System
10. Pain
11. Vision: The Eye
12. Central Visual Pathways
13. The Auditory System
14. The Vestibular System
15. The Chemical Senses

Unit III. Movement and Its Central Control

16. Lower Motor Neuron Circuits and Motor Control
17. Upper Motor Neuron Control of the Brainstem and Spinal Cord
18. Modulation of Movement by the Basal Ganglia
19. Modulation of Movement by the Cerebellum
20. Eye Movements and Sensory Motor Integration
21. The Visceral Motor System

Unit IV. The Changing Brain

22. Early Brain Develoment
23. Construction of Neural Circuits
24. Modification of Brain Circuits as a Result of Experience
25. Repair and Regeneration in the Nervous System

Unit V. Complex Brain Functions

26. The Association Cortices
27. Speech and Language
28. Sleep and Wakefulness
29. Emotions
30. Sex, Sexuality, and the Brain
31. Memory

Appendix: Survey of Human Neuroanatomy Back to top

Media and Supplements

For Students

Companion Website
(www.sinauer.com/neuroscience4e)

New for the Fourth Edition, the Neuroscience companion website features review and study tools to help your students master the material presented in the neuroscience course. Access to the site is free of charge and requires no passcode. The site includes:

• Chapter Summaries: Concise overviews of the important topics covered in each chapter.
• Animations: All new for the Fourth Edition, this collection of detailed animations depicts many of the key topics discussed in the textbook. Topics such as synaptic transmission, resting membrane potential, information processing in the eye, the stretch reflex, and many others are presented in a dynamic manner that helps students visualize and better understand many of the complex processes of neuroscience.
• Online Quizzes: For each chapter of the textbook, the companion site includes a multiple-choice quiz that covers all the main topics presented in the chapter. At the instructor’s discretion, these quizzes can be used either as self-review exercises or as assignments. (Instructor registration is required for student access to the quizzes.)
• Flashcards: Flashcard activities help students master the extensive vocabulary of neuroscience. Each chapter’s set of flashcards includes all the key terms introduced in that chapter.

Sylvius 4: Interactive Atlas and Visual Glossary of the Human Central Nervous System

S. Mark Williams, Leonard E. White, and Andrew C. Mace

The new Sylvius 4 provides a unique computer-based learning environment for exploring and understanding the structure of the human central nervous system. Sylvius features fully annotated surface views of the human brain, as well as interactive tools for dissecting the central nervous system and viewing fully annotated cross-sections of preserved specimens and living subjects imaged by magnetic resonance. This newly expanded and reconfigured Sylvius is more than a conventional atlas; it incorporates a comprehensive, visually rich, searchable database of more than 500 neuroanatomical terms that are concisely defined and visualized in photographs, magnetic resonance images, and illustrations from Neuroscience, Fourth Edition. For users familiar with its predecessors, this version of Sylvius unites the atlas content and utility of SylviusPro (and earlier versions of Sylvius) with the reference content of SylviusVG (and Sylvius for Neuroscience), making this version of Sylvius a single source for teaching and understanding the organization of the human central nervous system.

The new Sylvius is an excellent resource for neuroscience educators, medical students, physical therapy students, other postgraduate and professional learners, as well as undergraduate pre-medical and biological psychology students.

PROGRAM COMPONENTS

• Surface Anatomy Atlases—Provide a visual introduction to the location and names of the major external features and subdivisions of the human brain
• Photographic Atlas: Digitally enhanced photographic images of a human brain specimen
• Magnetic Resonance Image Atlas: High-resolution 3D reconstructions of a human brain specimen illustrating the major surface features
• Brainstem Model: 3D views of a widely used model illustrating the surface features of the brainstem as well as the location of cranial nerve nuclei
• Sectional Anatomy Atlases—Allow the user to explore the internal organization of the brain
• Photographic Atlas: Allows the student to “virtually dissect” a human brain specimen in the three standard planes (coronal, axial and sagittal)
• Magnetic Resonance Image Atlas: High-resolution in vivo atlas comprised of coronal, axial and sagittal sections, newly expanded to include complete series of sections in each anatomical plane
• Brainstem and Spinal Cord: A high-resolution, cross-sectional histological atlas of the human spinal cord and brainstem allowing students to examine principal tracts and nuclei
• Pathways—Allows students to follow the flow of information in several important long-tract pathways of the central nervous system
• Visual Glossary—Searchable glossary providing visual representations, concise anatomical and functional definitions, and audio pronunciation of neuroanatomical structures

ADDITIONAL FEATURES

• High-resolution color digital images of human brain specimens and sections
• Zoom feature for detailed inspection of brain images
• Notes feature: user can type notes for any selected structure; notes are automatically saved on the user’s computer; ideal for capturing course-specific annotations to Sylvius’ definitions
• Audio pronunciation of neuroanatomical terms
• Self-quiz mode
• User-defined preferences
• Image mark-up tools
• Image orientation reference
• View “at a glance” the 3D extent of structures via thumbnail slice navigator
• View multiple images at once
• Hierarchical grouping of neuroanatomical structures

For Instructors

Instructor’s Resource Library

Expanded for the Fourth Edition, the Neuroscience Instructor’s Resource Library includes a variety of resources to help in developing your course and delivering your lectures. The Library includes:

• Textbook Figures & Tables: All the figures and tables from the textbook are provided in JPEG format (both high- and low-resolution), reformatted and relabeled for optimal readability.
• PowerPoint^® Presentations: A PowerPoint presentation that includes all figures and tables is included for each chapter, making it easy to add figures to your own presentations.
• Sylvius Image Library: New for the Fourth Edition, a wide range of images from the companion program Sylvius 4 is included in PowerPoint format, for use in lecture.
• Animations: All of the animations from the companion website are included for use in lecture, and other course-related activities.
• Quiz Questions: All of the questions from the new companion website’s online quizzes are provided in Microsoft^® Word^® format.
• Review Questions: A set of short-answer review questions is provided for each chapter of the textbook (Microsoft Word format).

Online Quizzing

New for the Fourth Edition, instructors have access to a bank of online quizzes that they can choose to assign or let their students use for self-review purposes. Instructors can use the quizzes as-is, or they can create their own quizzes using any combination of publisher-provided questions and their own questions. The online grade book stores quiz results, which can be downloaded for use in grade book programs.

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Reviews and Commentary

“Neuroscience is a remarkably well-organized and well-written text. It is highly accessible and easy to follow, which is impressive given the amount of detail and depth it provides. Each step of the way, explanations of complex concepts are accompanied by easy-to-follow graphics that on the one hand enhance deep understanding, and, on the other, make it easy to even just browse or skim. The book does an excellent job of bridging between molecular and molar levels of analysis, between basic and clinical science, and between the big picture and discrete detail. In other words, it keeps you grounded and allows you to understand how basic processes relate to cognition, emotion, and behavior, as well as to various forms of dysfunction. … I am definitely keeping a copy of Neuroscience on my desk, along with Lezak et al., Strauss et al., and all the other classics.”
—Yana Suchy, JINS

“As is the tradition with this book, current neuroanatomical and neurophysiological concepts are explained in detail and fully illustrated. The addition of current concepts on neuroplasticity and behavior, as well as the web resources, significantly enrich this edition. This is a worthy and affordable book for neuroscience students. … An excellent contribution to the study of neuroscience, deserving of its place in neurology, neurosurgery, and neurosciences libraries.”
—Celso Agner, Doody's Book Review

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Pricing and Options

Titles	Product Code	Price (USD)
Neuroscience, Fourth Edition	978-0-87893-697-7	$107.95	Purchase	Request Exam Copy
Purves: Neuroscience 4/e bundled with Moore & Stuart: Neurons in Action Bundle available in US and Canada only. This bundle includes: Neurons in Action 2: Tutorials and Simulations using NEURON Neuroscience, Fourth Edition	978-0-87893-554-3	$136.70	Purchase	Request Exam Copy
Neuroscience 4/e with Neuroanatomy Through Clinical Cases Bundle available in US and Canada only. This bundle includes: Neuroanatomy through Clinical Cases Neuroscience, Fourth Edition	978-0-87893-553-6	$163.70	Purchase	Request Exam Copy
Neuroanatomy through Clinical Cases, Second Edition bundled with Neuroscience, Fourth Edition Bundle available in US and Canada only. This bundle includes: Neuroanatomy through Clinical Cases, Second Edition Neuroscience, Fourth Edition	978-0-87893-382-2	$168.20	Purchase	Request Exam Copy
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