Errata
CHAPTER TWO: On page 100, the last full sentence should read: "For example, the Xist gene has no open reading frame, but is required for dosage compensation (X chromosome inactivation) in mammals, and is situated adjacent to the FMR1 gene that is implicated in fragile-X syndrome."
CHAPTER THREE: On page 173, second paragraph, juvenile hormone is incorrectly referred to as a 'polypeptide', instead of as a 'terpenoid'.
BOX 5.2: The squared term in the denominator of the trend test chi-square formula is misplaced outside the square bracket. It should be immediately inside the square bracket so that it is only the last (n1 + 2n2) term that is squared. The correct formula should be:
c2 = N[N(r1 + 2r2) - R(n1 + 2n2)2] / RS[N(n1 + 2n2) - (n1 + 2n2)2]
Also, the next sentence describing this formula should read:
"For the example given in the text, if none of the 302 alleles in the affected individuals were in homozygotes for the A allele (r0 = 127, r1 = 24, r2 = 0), while 9 of the 382 alleles in the unaffecteds were in homozygotes (s0 = 114, s1 = 68, r2 = 9), then c2 = 32.8."
This minor correction of the r0 and s0 values results in a c2 value of 26.4 instead of 27.8 in the next paragraph.
BOX 5.3: The formula for the Family-based TDT also has a mis-placed bracket, such that the numerator should be
b - [(b+c)/2]
rather than
[b-(b+c)]/2 .
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